As a community leader and on behalf of the Custom Companies, Perry Mandera has donated his time, heart and dollars to many charitable organizations throughout the years. Specifically, Perry has focussed his charitable efforts on children's organizations and cancer prevention, some organizations include:
- The Walter and Connie Payton Foundation [Board Member]
- Jesse White Tumblers [Board Member]
- American Cancer Society
- Muscular Dystrophy Association [MDA]
- Y-Me
- Hurricane Katrina Relief
- Hurricane Wilma Relief
- Boys & Girls Club of America
- Lynn Sage Cancer Fund
- Kidss for Kids
- Ongoing sponsorships for youth team sports
- Catholic Charities
- Aids Research
- Juvenile Diabetes Research Foundation
- Rainbows Charities
- Leukemia & Lymphoma Society
- Special Olympics
- Youth Burn Camp
- Save our Seniors Foundation
- The University of Chicago Hospital
- The Erie House St. Joseph Day Food Handout
- The Boy Scouts and Girl Scouts of America
- The Chicago Anti-Hunger Federation
- WBBM News Radio Drug & Alcohol Prevention
- MADD
Perry Mandera was also instrumental in starting The Custom Companies own charitable organization - "Custom Cares Charities" [a 501(c)(3) organization], focussed on children's charities.